Variation in FTO contributes to childhood obesity and severe adult obesity

We identified a set of SNPs in the first intron of the FTO (fat mass and obesity associated) gene on chromosome 16q12.2 that is consistently strongly associated with early-onset and severe obesity in both adults and children of European ancestry with an experiment-wise P value of 1.67 x 10(-26) in 2,900 affected individuals and 5,100 controls. The at-risk haplotype yields a proportion of attributable risk of 22% for common obesity. We conclude that FTO contributes to human obesity and hence may be a target for subsequent functional analyses.     

建设项目造价控制初探

介绍了建设项目造价控制的内容、措施,提出了加强工程审计环节的控制措施。     

基于网络的英语口语教学体系的构建

分析了建立基于网络的英语口语教学体系的必要性及可行性,提出了建立体系平台框架的设想。     

有机染料中间体对乙酰氨基苯磺酰氯的合成工艺改进

在乙酰苯胺氯磺酰化合成对乙酰氨基苯磺酰氯的反应工艺中,反应后期加入硫酸钠.探讨了反应物摩尔比、反应温度、时间、溶剂和硫酸钠等因素对产率的影响,确定了最佳原料摩尔比:乙酰苯胺∶氯磺酸=1∶4.3.改进后,氯磺化的收率明显提高,废弃物排放量减小.     

基于反相对称法的双边带通信系统

给出了一种基于反相对称法的双边带通信系统的实现方法,通过MATLAB仿真,证实了这种方法的可行性。     

有限个一致李普希兹渐近拟非扩张映像强收敛定理

在任意Banach空间中,给出了有限个一致李普希兹渐近拟非扩展映像强收敛于其公共不动点的问题,此结果推广了以前的结论.     

双寡头古诺生产模型的自适应控制

将自适应控制方法应用到二维多参数的古诺生产模型,其控制目标是通过对控制参数的小扰动将系统引导到不稳定不动点或均衡点.理论推导和数值模拟结果说明了此方法不管是对一个参数还是对多个参数施加扰动都能成功地将混沌不稳定轨道稳定到低周期轨道,并解析地给出了收敛条件和控制强度所在的范围.实施控制后的生产模型能快速地达到Nash均衡点,这为现实中的企业提供了理论参考及生产依据.     

Preface

Different from traditional tax audit, supervision with self-audit is a combination of audit by the taxpayer himself and audit by the tax authority. This paper mainly studies a taxpayer’s optimal policy of tax evasion under supervision with self-audit and its related properties, in order to deduce some effective suggestions and theoretical bases to restrain tax evasion. Assuming that only a certain proportion of evaded tax can be discovered when the audit is executed, the authors first formulate a static model with self-audit. This model is divided into two stages. At the first stage, taxpayers declare their taxes, then the tax authority chooses audit objects, based on a known probability, and announces the result; if the taxpayer is chosen, he will enter the second stage, during which he has a chance to pay the evaded tax and the corresponding late fees and then is audited by the tax authority. The authors show the existence and uniqueness of the optimal amount of tax evasion at the first stage and the optimal proportion to self-expose at the second stage. The authors also discuss the related properties of the interior solution, and do elasticity analyses on some parameters. Besides, the authors extend the static model into the corresponding two-period model, and study the existence and uniqueness of the solution of the extended model. Finally, under the assumption that tax evasion can only be discovered with a certain probability when the audit is executed, the authors formulate another static model with self-audit and investigate its properties. This research is partially supported by the National Natural Science Foundation of China under Grant Nos. 60674082, 70221001, and 70731003.     

论企业产权与会计信息失真

从会计和产权的角度出发,分析了我国会计信息失真原因,提出了相应的治理措施。     

对卷烟零售终端的分析及控制方法的探讨

探讨了烟草销售行业改革的迫切性,分析了卷烟零售终端中存在的问题,提出了解决这些问题的办法,并探讨了建设网络销售终端的优势。